"Kolodko ... has been disqualified from the Olympic Games London 2012 in which she ranked second and for which she was awarded the silver medal," the IOC said in a statement on Sunday.
"Reanalysis of Kolodko's samples from London 2012 resulted in a positive test for the prohibited substances dehydrochlormethyltestosterone (turinabol) and ipamorelin."
Kolodko was upgraded to London Olympics silver medal following a disqualification of the gold medal winner Belarus Nadezhda Ostapchuk.
Now after Kolodko's disqualification Chinese athletes Gong Lijiao and Li Ling will be upgraded to silver and bronze respectively.
Earlier this week Russians were stripped of from London Olympics women's 4x400m and 4x100m medals after re-analysis showed prohibited substances in more Russian athletes.
The IOC started retesting stored doping samples from London Olympics. Until now 98 doping samples have returned positive results. Majority of positive tests come from Russian athletes.
Last year in November the track and field governing body IAAF banned Russian Athletics Federation from international competition after accusations of of state-sponsored doping.
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