| Time: US Eastern | Official Starts |
|---|---|
| 8:30 a.m. | Professional Wheelchair Division |
| 8:52 a.m. | Achilles Handcycle Category and Select Athletes with Disabilities |
| 8:55 a.m. | Foot Locker Five-Borough Challenge |
| 9:20 a.m. | Professional Women |
| 9:50 a.m. | Wave 1 (including Professional Men) |
| 10:15 a.m. | Wave 2 |
| 10:40 a.m. | Wave 3 |
| 11:00 a.m. | Wave 4 |
16 April 2021 02:40 (GMT)
17 April 2021 22:00 (GMT)
18 April 2021 06:30 (GMT)
23 April 2021 19:00 (GMT)
01 May 2021 16:30 (GMT)