The 400m Olympic champion, Miller-Uibo, clcoked 16.23 to shave 0.07 of a second off the mark that American Tori Bowie set in the same meet last year.
“The 150, it’s go from the get-go for me,” Miller-Uibo said.
Last year at inaugural Boost Boston Games the Bahamian set a new World record in a straight 200m with 21.76.
Bahamian athletes celebrated another victory at Boost Boston Games on Sunday as Steven Gardiner clocked 19.88 seconds to win the race way ahead of Panama's Alonso Edwards (20.03).
Great Britains Zharnel Hughes clocked 9.99 seconds to win the men's 100m dash, while Tori Bowie of the United States took the win in the women's 100m with 11.05 seconds.
01 December 2022 22:30 (GMT)
02 December 2022 17:00 (GMT)
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11 December 2022 10:00 (GMT)