The Rio Olympics champion Van Niekerk proved he is ready to replace legendary Usain Bolt after he comfortably clocked 19.84 seconds to win the 200m on a specially built elevated track on Boston's Charles Street that allowed fans to watch up close.
"I've still got a lot of work to do and have a lot of areas I need to look into," Van Niekerk told reporters. "But it was a positive win for me today." the world record holder in 400m added.
Earlier this year Van Niekerk announced that he will attempt the 200m and 400m double at the IAAF World Championships in London in August.
American sprinter Tori Bowie set a new world record in a rarely run 150m dash with 16.30 seconds. Watch race here.
The women's 200m dash was won by the Olympic 400m champion Shaunae Miller-Uibo of Bahamas in 21.76 seconds.
Former 100m champion, Yohan Blake, of Jamiaca was beaten into 3rd place in the men's 150m dash. Alonso Edward of Panama took the 150m race in 15.09 with Nickel Ashmeade of Jamiaca crossing the line in 2nd in 15.16 and Blake in 3rd in 15.17.
Trinind and Tobago athletes rulled men's and women's 100m races. Kelli-Ann Baptiste won the women's 100m dash with a time of 11.06 while her teammate Michelle-Lee Ahye finished in 2nd in 11.11. Keston Bledman claimed a dramatic men's 100m street race in 10.21 just 0.001 seconds ahead of South Africa's sprint star Akani Simbine.
For full meet results see page here.
Wayde van Niekerk 19.84 (0.6) misses 200m WORLD RECORD! while slowing down
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